Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGCGGSRADA IEPRYYESWT RETESTWLTY TDSDAPPSAA APDSGPEAGG LHSGMLEDGL PSNGVPRSTA PGGIPNPEKK TNCETQCPNP QSLSSGPLTQ KQNGLQTTEA KRDAKRMPAK EVTINVTDSI QQMDRSRRIT KNCVN
    • Molecular weight
      18 kDa including tags
    • Amino acids
      1 to 145
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab117684 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab117684 is purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Additional notes
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 20% Glycerol, 0.06% EDTA

General Info

  • Alternative names
    • BAALC
    • BAALC_HUMAN
    • Brain and acute leukemia cytoplasmic
    • Brain and acute leukemia cytoplasmic protein
    • FLJ12015
    see all
  • Function
    May play a synaptic role at the postsynaptic lipid rafts by interacting with CAMK2A.
  • Tissue specificity
    Expressed by neural and hematopoietic cells. Expression is found both in normal early progenitor cells and in the most immature type of blasts in acute leukemia but not in mature hematopoietic cells. Isoform 2 and isoform 6 are expressed in the brain. Isoform 2 shows a low expression in neuroectoderm-derived tissues such as adrenal gland and no expression in bone marrow, peripheral blood lymphocytes or lymph nodes, or in tumors or cancer cell lines of nonneural tissue origin.
  • Post-translational
    modifications
    Palmitoylation and myristoylation target the protein to the lipid rafts.
  • Cellular localization
    Cytoplasm. Membrane. Postsynaptic lipid rafts.
  • Information by UniProt

References for Recombinant Human BAALC protein (ab117684)

ab117684 has not yet been referenced specifically in any publications.

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