Overview

  • Product nameRecombinant Human BAPX1 protein
  • Protein lengthProtein fragment

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • Accessionp78367
    • SpeciesHuman
    • SequenceRLFGERDAGALGGAEDSLLASPAGTRTAAGRTAESPEGWDSDSALSEENE SRRRCADAR
    • Molecular weight32 kDa including tags
    • Amino acids53 to 111

Specifications

Our Abpromise guarantee covers the use of ab114496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Bagpipe homeobox 1
    • Bagpipe homeobox homolog 1
    • Bagpipe homeobox protein homolog 1
    • Bagpipe homeobox, Drosophila, homolog of, 1
    • BAPX 1
    • Homeobox protein NK-3 homolog B
    • Homeobox protein Nkx 3.2
    • Homeobox protein Nkx-3.2
    • MGC138171
    • NK3 homeobox 2
    • NKX3 2
    • NKX3-2
    • NKX3.2
    • NKX3.2, mouse, homolog of
    • NKX32_HUMAN
    • NKX3B
    • OTTHUMP00000115816
    • SMMD
    see all
  • FunctionTranscriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus.
  • Tissue specificityExpressed at highest levels in cartilage, bone (osteosarcoma) and gut (small intestine and colon), whereas moderate expression is seen in trachea and brain. Expressed in visceral mesoderm and embryonic skeleton.
  • Involvement in diseaseDefects in NKX3-2 are the cause of spondylo-megaepiphyseal-metaphyseal dysplasia (SMMD) [MIM:613330]. It is a skeletal dysplasia characterized by disproportionate short stature with a short and stiff neck and trunk, relatively long limbs that may show flexion contractures of the distal joints, delayed and impaired ossification of the vertebral bodies, the presence of large epiphysea ossification centers and wide growth plates in the long tubular bones and numerous pseudoepiphyses of the short tubular bones in hands and feet.
  • Sequence similaritiesBelongs to the NK-3 homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localizationNucleus.
  • Information by UniProt

Recombinant Human BAPX1 protein images

  • ab114496 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

References for Recombinant Human BAPX1 protein (ab114496)

ab114496 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"