The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20ºC.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride
Reconstitute with water to desired concentration.
BRCA2 and CDKN1A interacting protein
BRCA2 and CDKN1A-interacting protein
BRCA2 and Cip1/p21 interacting protein
Cdk inhibitor p21 binding protein
P21 and CDK associated protein 1
P21- and CDK-associated protein 1
May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ).
Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen.
Belongs to the BCP1 family.
Isoform 1 is expressed throughout the cell cycle. Isoform 2 is expressed following mitosis and peaks in the G1/S phase of the cell cycle.
Nucleus. Colocalizes with BRCA2 in discrete nuclear foci.