Recombinant Human Bcl2A1 protein (ab126683)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSHMTDCEF GYIYRLAQDY LQYVLQIPQP GSGPSKTSRV LQKVAFSVQK EVEKNLKSCL DNVNVVSVDT ARTLFNQVME KEFEDDIINW GRIVTIFAFE GILIKKLLRQ QIAPDVDTYK EISYFVAEFI MNNTGEWIRQ NGGWENGFVK KFEPKS
    • Molecular weight
      20 kDa including tags
    • Amino acids
      1 to 152
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab126683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 95 % SDS-PAGE.
    ab126683 is purified using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

General Info

  • Alternative names
    • ACC 1
    • ACC 2
    • B2LA1_HUMAN
    • Bcl 2 related protein A1
    • Bcl-2-like protein 5
    • Bcl-2-related protein A1
    • BCL2 related protein A1
    • Bcl2-L-5
    • BCL2A1
    • BCL2L5
    • BFL1
    • GRS
    • HBPA1
    • Hematopoietic BCL2 related protein A1
    • Hemopoietic specific early response protein
    • Hemopoietic-specific early response protein
    • Protein BFL 1
    • Protein BFL-1
    • Protein GRS
    see all
  • Function
    Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection.
  • Tissue specificity
    Seems to be restricted to the hematopoietic compartment. Expressed in peripheral blood, spleen, and bone marrow, at moderate levels in lung, small intestine and testis, at a minimal levels in other tissues. Also found in vascular smooth muscle cells and hematopoietic malignancies.
  • Sequence similarities
    Belongs to the Bcl-2 family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab126683 (3 µg)

References

ab126683 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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