Recombinant human beta 4 Defensin protein (ab123837)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
    • Molecular weight
      6 kDa
    • Amino acids
      23 to 72

Specifications

Our Abpromise guarantee covers the use of ab123837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Determined by its ability to chemoattract Human monocytes using a concentration range of 0.1-50 ng/ml.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 98 % SDS-PAGE.
    ab123837 is purified by proprietary chromatographic techniques. Purity is greater than 98% as determined by HPLC and SDS-PAGE.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 7.40
    Constituents: 99% PBS, 0.76% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in sterile dd water to a concentration = 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.

General Info

  • Alternative names
    • BD 4
    • BD-4
    • BD4
    • beta 104
    • Beta defensin 4
    • Beta-defensin 104
    • Beta-defensin 4
    • D104A_HUMAN
    • DEFB-4
    • DEFB104B
    • Defensin
    • Defensin beta 104
    • Defensin beta 4 precursor
    • hBD 4
    • hBD-4
    • hBD4
    see all
  • Function
    Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
  • Tissue specificity
    High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.
  • Sequence similarities
    Belongs to the beta-defensin family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References for Recombinant human beta 4 Defensin protein (ab123837)

ab123837 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123837.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up