Recombinant human beta 4 Defensin protein (ab123837)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      EFELDRICGY GTARCRKKCR SQEYRIGRCP NTYACCLRKW DESLLNRTKP
    • Molecular weight
      6 kDa
    • Amino acids
      23 to 72

Specifications

Our Abpromise guarantee covers the use of ab123837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activity
    Determined by its ability to chemoattract Human monocytes using a concentration range of 0.1-50 ng/ml.
  • Applications

    Functional Studies

    SDS-PAGE

  • Purity
    > 98 % SDS-PAGE.
    ab123837 is purified by proprietary chromatographic techniques. Purity is greater than 98% as determined by HPLC and SDS-PAGE.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

    pH: 7.40
    Constituents: 99% PBS, 0.76% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Centrifuge the vial prior to opening. Reconstitute in sterile dd water to a concentration = 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use.

General Info

  • Alternative names
    • BD 4
    • BD-4
    • BD4
    • beta 104
    • Beta defensin 4
    • Beta-defensin 104
    • Beta-defensin 4
    • D104A_HUMAN
    • DEFB-4
    • DEFB104B
    • Defensin
    • Defensin beta 104
    • Defensin beta 4 precursor
    • hBD 4
    • hBD-4
    • hBD4
    see all
  • Function
    Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103.
  • Tissue specificity
    High expression in the testis. Gastric antrum exhibited relatively high levels. A lower expression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression in other tissues tested.
  • Sequence similarities
    Belongs to the beta-defensin family.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab123837 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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