The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesBest use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione
cardiomyopathy, hypertrophic 1
Myosin heavy chain, cardiac muscle beta isoform
myosin, heavy polypeptide 7, cardiac muscle, beta
RelevanceMuscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.
Cellular localizationThick filaments of the myofibrils.
Recombinant Human beta-cardiac myosin heavy chain protein images
SDS-PAGE - beta-cardiac myosin heavy chain protein (ab112326)
ab112326 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.
References for Recombinant Human beta-cardiac myosin heavy chain protein (ab112326)
has not yet been referenced specifically in any publications.
Publishing research using ab112326? Please let us know so that we can cite the reference in this datasheet.
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