Recombinant human beta Defensin 3 protein (ab50059)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • Amino acids1 to 45

Associated products

Specifications

Our Abpromise guarantee covers the use of ab50059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitute to 1mg/ml using sterile water.

General Info

  • Alternative names
    • BD 3
    • BD-3
    • BD3
    • beta 103
    • Beta defensin 103A
    • Beta defensin 103A precursor
    • Beta defensin 3
    • Beta-defensin 103
    • Beta-defensin 3
    • D103A_HUMAN
    • DEF B3
    • DEFB 103
    • DEFB 103A
    • DEFB 3
    • DEFB-3
    • DEFB103
    • DEFB103A
    • DEFB103B
    • DEFB3
    • Defensin
    • Defensin beta 103A
    • Defensin beta 3
    • Defensin like protein
    • Defensin-like protein
    • HBD 3
    • hBD-3
    • HBD3
    • HBP 3
    • HBP3
    • mBD3
    see all
  • FunctionExhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
  • Tissue specificityHighly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.
  • Sequence similaritiesBelongs to the beta-defensin family.
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human beta Defensin 3 protein (ab50059)

ab50059 has not yet been referenced specifically in any publications.

Product Wall

Thank you for sending along the dot blots and additional information. We really appreciate the extra troubleshootingeffort.

Here are my thoughts:

1. In general it looks like the antibodies are able to detect Defensin in the chorioam...

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Thank you for contacting Abcam Technical Team and for taking the time to provide some useful details of the experiments. I am very sorry to hear that your customer is are having problems with 8 of our products.  Special thanks for collecting the troubl...

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Thank you for your reply. Unfortunately, we do not have information about the folding/3D structure of ab50059. We did not perform any testing on the specific folding structure to determine the 3D structure of this protein. However, technicall...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"