Recombinant Human Bile salt-activated lipase protein (ab114625)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionQ86SR3
    • SpeciesHuman
    • SequenceGLRGAKTTFDVYTESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHR ANAKSAKTYAYLFSHPSRMPVYPKWVGADHADDIQYVFGKPFATPTGYRP
    • Molecular weight37 kDa including tags
    • Amino acids378 to 477

Specifications

Our Abpromise guarantee covers the use of ab114625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • FormLiquid
  • Additional notesProtein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

General Info

  • Alternative names
    • BAL
    • Bile salt-stimulated lipase
    • BSDL
    • BSSL
    • Bucelipase
    • Carboxyl ester lipase
    • Carboxyl ester lipase (bile salt stimulated lipase)
    • CEase
    • CEL
    • CELL
    • Cholesterol esterase
    • FAP
    • FAPP
    • Fetoacinar pancreatic protein
    • LIPA
    • Lysophospholipase, pancreatic
    • MODY8
    • Pancreatic lysophospholipase
    • Sterol esterase
    see all
  • RelevanceDefects in Bile salt activated lipase (CEL) are a cause of maturity onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:609812], also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY [MIM:606391] is an autosomal dominant form of diabetes mellitus. The pancreas serves both endocrine and exocrine functions. The endocrine cells are found in the islets of Langerhans. They synthesize insulin and other hormones, and are involved in the pathogenesis of diabetes mellitus. The exocrine cells produce bicarbonate and digestive enzymes and are involved in the pathogenesis of pancreatic malabsorption. The localization of the islets within exocrine pancreatic tissue is suggestive of an interdependency and cross talk between these two cell populations in their normal and in their abnormal function.
  • Cellular localizationCytoplasmic and Nuclear

Recombinant Human Bile salt-activated lipase protein images

  • ab114625 analysed on a 12.5% SDS-PAGE stained with Coomassie Blue.

References for Recombinant Human Bile salt-activated lipase protein (ab114625)

ab114625 has not yet been referenced specifically in any publications.

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