B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
Expressed in brain and other neural tissues.
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.