Recombinant Human BLOC1S2 protein (ab126912)

Overview

  • Product name
    Recombinant Human BLOC1S2 protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MGSHMAAAAE GVLATRSDEP ARDDAAVETA EEAKEPAEAD ITELCRDMFS KMATYLTGEL TATSEDYKLLENMNKLTSLK YLEMKDIAIN ISRNLKDLNQ KYAGLQPYLD QINVIEEQVA ALEQAAYKLD AYSKKLEAKY KKLEKR
    • Molecular weight
      19 kDa including tags
    • Amino acids
      1 to 142
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab126912 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    < 85 % SDS-PAGE.
    ab126912 is purified by conventional chromatography techniques to > 85% by SDS - PAGE.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

General Info

  • Alternative names
    • Biogenesis of lysosome-related organelles complex 1 subunit 2
    • BL1S2_HUMAN
    • BLOC-1 subunit 2
    • Bloc1s2
    • BLOS2
    • Centrosome-associated protein
    • RP11 316M21.4
    see all
  • Function
    May play a role in cell proliferation. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking.
  • Tissue specificity
    Isoform 1 and isoform 2 are widely expressed. Expressed in various malignant tumor tissues (at protein level).
  • Sequence similarities
    Belongs to the BLOC1S2 family.
  • Cellular localization
    Cytoplasm > cytoskeleton > centrosome. Localizes to the centrosomes in a microtubule-dependent manner.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab126912 (3 µg). Please note: Molecular weight on SDS-PAGE will appear higher.

References

ab126912 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab126912.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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