Recombinant Human Blood Group Antigen Precursor protein (ab113153)

Overview

  • Product name
    Recombinant Human Blood Group Antigen Precursor protein
  • Protein length
    Full length protein

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      37 kDa
    • Amino acids
      54 to 354
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab113153 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Mass Spectrometry

  • Mass spectrometry
    MALDI-TOF
  • Purity
    > 85 % SDS-PAGE.
    ab113153 was purified using conventional chromatography techniques.
  • Form
    Liquid
  • Additional notes


  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.04% DTT, 20% Glycerol, 1.17% Sodium chloride

General Info

  • Alternative names
    • A transferase
    • A3GALNT
    • A3GALT1
    • Abo
    • ABO A3 transferase
    • ABO blood group (transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase)
    • ABO glycosyltransferase
    • ABO weak transfer
    • B (A) alpha 1, 3 glactosyltransferase
    • B transferase
    • BGAT_HUMAN
    • Fucosylglycoprotein 3 alpha galactosyltransferase
    • Fucosylglycoprotein 3-alpha-galactosyltransferase
    • Fucosylglycoprotein alpha N acetylgalactosaminyltransferase
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase
    • Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form
    • Glycoprotein fucosylgalactoside alpha galactosyltransferase
    • Glycoprotein fucosylgalactoside alpha N acetylgalactosaminyltransferase
    • Glycoprotein-fucosylgalactoside alpha-galactosyltransferase
    • Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase
    • GTB
    • Histo blood group A transferase
    • Histo blood group A2 transferase
    • Histo blood group ABO system transferase
    • Histo blood group B transferase
    • Histo-blood group A transferase
    • Histo-blood group B transferase
    • NAGAT
    see all
  • Function
    This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
  • Pathway
    Protein modification; protein glycosylation.
  • Sequence similarities
    Belongs to the glycosyltransferase 6 family.
  • Domain
    The conserved DXD motif is involved in cofactor binding. The manganese ion interacts with the beta-phosphate group of UDP and may also have a role in catalysis.
  • Post-translational
    modifications
    The soluble form derives from the membrane form by proteolytic processing.
  • Cellular localization
    Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
  • Information by UniProt

Images

  • 15% SDS-PAGE showing ab113153 (3 µg) at approximately 37.4 kDa

References

ab113153 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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