Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MAVKKIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHV VVGDVLQAADVDKTVAGQDAVIVLLGTRNDLSPTTVMSEGARNIVAAMKA HGVDKVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLKYVAVM PPHIGDQPLTGAYTVTLDGRGPSRVISKHDLGHFMLRCLTTDEYDGHSTY PSHQYQ
    • Molecular weight
      22 kDa
    • Amino acids
      1 to 206

Specifications

Our Abpromise guarantee covers the use of ab117187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab117187 is purified by proprietary chromatographic techniques.
  • Form
    Liquid
  • Additional notes
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Please see notes section.

    pH: 8.50
    Constituents: 0.32% Tris HCl, 10% Glycerol, 0.02% DTT

General Info

  • Alternative names
    • Biliverdin IX beta reductase
    • Biliverdin reductase B
    • biliverdin reductase B (flavin reductase (NADPH))
    • Biliverdin-IX beta-reductase
    • BLVRB
    • BLVRB_HUMAN
    • BVR B
    • BVR-B
    • BVRB
    • epididymis secretory protein Li 10
    • Flavin reductase
    • Flavin reductase (NADPH)
    • FLR
    • FR
    • GHBP
    • Green heme binding protein
    • Green heme-binding protein
    • HEL-S-10
    • Methemoglobin reductase
    • MGC117413
    • NADPH dependent diaphorase
    • NADPH flavin reductase
    • NADPH-dependent diaphorase
    • NADPH-flavin reductase
    • SDR43U1
    • short chain dehydrogenase/reductase family 43U, member 1
    see all
  • Function
    Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
  • Tissue specificity
    Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

References

ab117187 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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