Recombinant human BMP7 protein (ab50100)

Overview

Description

  • NatureRecombinant
  • SourceCHO cells
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMANVAENSSS DQRQACKKHE LYVSFRDLGW QDWIIAPEGY AAYYCEGECA FPLNSYMNAT NHAIVQTLVH FINPETVPKP CCAPTQLNAI SVLYFDDSSN VILKKYRNMV VRACGCH
    • Amino acids315 to 431

Specifications

Our Abpromise guarantee covers the use of ab50100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Endotoxin level< 0.100 Eu/µg
  • FormLyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • ReconstitutionReconstitution volume is lot specific. Please contact Scientific Support.

General Info

  • Alternative names
    • BMP 7
    • BMP-7
    • Bmp7
    • BMP7_HUMAN
    • Bone morphogenetic protein 7
    • Bone morphogenic protein 7
    • Eptotermin alfa
    • OP 1
    • OP-1
    • OP1
    • Osteogenic protein 1
    see all
  • FunctionInduces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
  • Tissue specificityExpressed in the kidney and bladder. Lower levels seen in the brain.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Developmental stageExpressed in the developing eye, brain and ear during embryogenesis.
  • Post-translational
    modifications
    Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).
  • Cellular localizationSecreted.
  • Information by UniProt

References for Recombinant human BMP7 protein (ab50100)

ab50100 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us again.

It is recommended that further dilutions be made in PBS containing 2 mg/ml albumin and stored at -20C for future use.

I hope this information is helpful to you. Please do not hesitate to contact ...

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I am sorry that I have offended the customer, that was not my intention. As you probably know, if there is no note regarding the reconstitution buffer, the reconstitution buffer is just...

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Thank you for contacting us.

As we deliver this protein in a lyophilised form (10ug), the final concentration will depend on how much buffer volume the end-user will use to dissolve the protein.

I hope this information is helpful ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"