Recombinant Human BMP7 protein (ab87055)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant Human BMP7 protein
See all BMP7 proteins and peptides -
Purity
> 95 % SDS-PAGE.
ab87055 was purified using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer. -
Expression system
Escherichia coli -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
MSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH LEHHHHHH -
Amino acids
293 to 431
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab87055 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Additional notes
Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method) -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 3.50
Constituents: 0.294% Sodium citrate, 10% Glycerol (glycerin, glycerine)
General Info
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Alternative names
- BMP 7
- BMP-7
- Bmp7
see all -
Function
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. -
Tissue specificity
Expressed in the kidney and bladder. Lower levels seen in the brain. -
Sequence similarities
Belongs to the TGF-beta family. -
Developmental stage
Expressed in the developing eye, brain and ear during embryogenesis. -
Post-translational
modificationsSeveral N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014). -
Cellular localization
Secreted. - Information by UniProt
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab87055 has been referenced in 1 publication.
- Zhang H et al. Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. Cell Res 27:1157-1177 (2017). PubMed: 28809397