Overview

Description

  • Nature
    Recombinant
  • Source
    Baculovirus infected Sf9 cells
  • Amino Acid Sequence
    • Species
      Human

Specifications

Our Abpromise guarantee covers the use of ab60877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Form
    Liquid
  • Additional notes

    ab204877 (Poly (4:1 Glu, Tyr) peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Bmx
    • BMX non receptor tyrosine kinase
    • BMX_HUMAN
    • BONE MARROW KINASE, X-LINKED
    • Bone marrow tyrosine kinase gene in chromosome X protein
    • Cytoplasmic tyrosine protein kinase BMX
    • Cytoplasmic tyrosine-protein kinase BMX
    • Epithelial and endothelial tyrosine kinase
    • ETK
    • NKT38
    • NTK 38
    • NTK38
    • Protein tyrosine kinase BMX
    • PSCTK 2
    • PSCTK 3
    • PSCTK2
    • PSCTK3
    see all
  • Function
    Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.
  • Tissue specificity
    Preferentially expressed in epithelial and endothelial cells.
  • Sequence similarities
    Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
    Contains 1 Btk-type zinc finger.
    Contains 1 PH domain.
    Contains 1 protein kinase domain.
    Contains 1 SH2 domain.
  • Domain
    SH2 domain mediates interaction with RUFY1.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • Sample Kinase Activity Plot.
  • ab60877 on SDS-PAGE, MW ~110 kDa.

References

ab60877 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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