The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Adenovirus E1B19k binding protein B5
Adenovirus E1B19K-binding protein B5
BCL2/adenovirus E1B 19 kd protein interacting protein 3a
BCL2/adenovirus E1B 19 kDa protein interacting protein 3A
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A
BCL2/adenovirus E1B 19kDa interacting protein 3 like
NIP3 like protein X
NIP3-like protein X
FunctionInduces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor suppressor. Inhibits apoptosis induced by BNIP3.
Sequence similaritiesBelongs to the NIP3 family.
Post-translational modificationsUndergoes progressive proteolysis to an 11 kDa C-terminal fragment, which is blocked by the proteasome inhibitor lactacystin.