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Amino Acid Sequence
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
- 2,3-bisphosphoglycerate mutase
- 2,3-bisphosphoglycerate mutase, erythrocyte
Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 126.96.36.199) and phosphatase (EC 188.8.131.52) activities.
Involvement in disease
Defects in BPGM are the cause of bisphosphoglycerate mutase deficiency (BPGMD) [MIM:222800]. A disease characterized by hemolytic anemia, splenomegaly, cholelithiasis and cholecystitis.
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Glycation of Lys-159 in diabetic patients inactivates the enzyme.
Information by UniProt
Recombinant Human BPGM protein images
References for Recombinant Human BPGM protein (ab95344)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"