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Amino Acid Sequence
MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLEVLFQGPLGSPSKPGRKTNQLQYMQNVVV KTLWKHQFAWPFYQPVDAIKLNLPDYHKIIKNPMDMGTIKKRLENNYYWS ASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQKVAQMPQEEVEL LPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIA ATPVPTITANVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKAD TTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPKKDLEDGE VPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHD YHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEV VAMARKLQDVFEMRFAKMPD
70 kDa including tags
29 to 417
GST tag N-Terminus
Additional sequence information
Bromodomains 1 and 2 (NM_007371).
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
BRD3 protein is incubated with biotinylated acetyl-histone peptide substrate in BRD assay buffer in a 10 µl reaction for 30 min at RT.
Concentration information loading...
Stability and Storage
Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.
Constituents: 0.63% Tris HCl, 0.64% Sodium chloride, 0.02% Potassium chloride, 20% Glycerol
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Involvement in disease
Note=A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.
Contains 2 bromo domains.
Information by UniProt
Functional Studies - Active human BRD3 protein fragment (ab196112)
ab196112 binding biotinylated acetyl-histone peptide substrate.
SDS-PAGE - Active human BRD3 protein fragment (ab196112)
4-20% SDS-PAGE analysis of 2 µg ab196112 with Coomassie staining.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"