The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl. Best use within three months from the date of receipt of this protein.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Brain specific homeobox POU domain protein 4
Brain-specific homeobox/POU domain protein 4
Octamer-binding protein 9
Octamer-binding transcription factor 9
POU class 3 homeobox 4
POU domain class 3 transcription factor 4
transcription factor 4
Probable transcription factor which exert its primary action widely during early neural development and in a very limited set of neurons in the mature brain.
Involvement in disease
Defects in POU3F4 are a cause of deafness X-linked type 2 (DFNX2) [MIM:304400]. A mixed type of deafness characterized by both conductive hearing loss resulting from stapes (perilymphatic gusher) fixation and progressive sensorineural deafness.
Belongs to the POU transcription factor family. Class-3 subfamily. Contains 1 homeobox DNA-binding domain. Contains 1 POU-specific domain.