The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
bruno like 6, RNA binding protein
Bruno like 6, RNA binding protein (Drosophila)
Bruno like protein 6
Bruno-like protein 6
CUG-BP- and ETR-3-like factor 6
CUGBP and ETR3 like factor 6
CUGBP Elav-like family member 6
RNA binding protein BRUNOL 6
RNA-binding protein BRUNOL-6
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
Belongs to the CELF/BRUNOL family. Contains 3 RRM (RNA recognition motif) domains.