The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab123192 is purified using conventional chromatography techniques.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00 Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol
Carbonic anhydrase related protein
Carbonic anhydrase VIII
Carbonic anhydrase-related protein
FunctionDoes not have a carbonic anhydrase catalytic activity.
Involvement in diseaseDefects in CA8 are the cause of cerebellar ataxia mental retardation and dysequilibrium syndrome type 3 (CMARQ3) [MIM:613227]. CMARQ3 is a congenital cerebellar ataxia associated with dysarthia, quadrupedal gait and mild mental retardation.
Sequence similaritiesBelongs to the alpha-carbonic anhydrase family.