Recombinant Human Calnexin protein (ab115706)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Molecular weight
      74 kDa
    • Amino acids
      1 to 592

Specifications

Our Abpromise guarantee covers the use of ab115706 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Purity
    >= 85 % SDS-PAGE.
    85% SDS-PAGE. ab115706 is purified by multi-step chromatography.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Constituents: 5% Glycerol, 0.06% Calcium chloride, Sodium chloride, Tris

General Info

  • Alternative names
    • Calnexin
    • CALX_HUMAN
    • CANX
    • CNX
    • FLJ26570
    • Histocompatibility complex class I antigen binding protein p88
    • IP90
    • Major histocompatibility complex class I antigen-binding protein p88
    • p90
    see all
  • Function
    Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.
  • Sequence similarities
    Belongs to the calreticulin family.
  • Cellular localization
    Endoplasmic reticulum membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Images

  • SDS-PAGE analysis of ab115706 stained with Coomassie.

    Lane 1: MW markers
    Lane 2: at 0.5 mg
    Lane 3: at 1 mg
    Lane 4: at 2 mg
    Lane 5: at 5 mg
  • All lanes : Calnexin - ER membrane marker at 1/1000 dilution

    Lane 1 : Recombinant Human Calnexin protein (ab115706) at 0.05 µg
    Lane 2 : Recombinant Human Calnexin protein (ab115706) at 0.1 µg

References

ab115706 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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