Recombinant Human Calumenin protein (ab116401)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • AccessionO43852
    • SpeciesHuman
    • SequenceMGSSHHHHHH SSGLVPRGSH MKPTEKKDRV HHEPQLSDKV HNDAQSFDYD HDAFLGAEEA KTFDQLTPEE SKERLGKIVS KIDGDKDGFV TVDELKDWIK FAQKRWIYED VERQWKGHDL NEDGLVSWEE YKNATYGYVL DDPDPDDGFN YKQMMVRDER RFKMADKDGD LIATKEEFTA FLHPEEYDYM KDIVVQETME DIDKNADGFI DLEEYIGDMY SHDGNTDEPE WVKTEREQFV EFRDKNRDGK MDKEETKDWI LPSDYDHAEA EARHLVYESD QNKDGKLTKE EIVDKYDLFV GSQATDFGEA LVRHDEF.
    • Molecular weight37 kDa including tags
    • Amino acids20 to 315
    • TagsHis tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab116401 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 90 % SDS-PAGE.
    ab116401 was purified by proprietary chromatographic techniques.
  • FormLiquid
  • Additional notesFor long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 10% Glycerol, 0.32% Tris HCl

General Info

  • Alternative names
    • CALU
    • CALU_HUMAN
    • Calumenin
    • Calumenin 1
    • Calumenin 2
    • Crocalbin
    • crocalbin-like protein
    • FLJ90608
    • IEF SSP 9302
    • multiple EF-hand protein
    • OTTHUMP00000212712
    • OTTHUMP00000212713
    • OTTHUMP00000212714
    • OTTHUMP00000212715
    see all
  • FunctionInvolved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
  • Tissue specificityUbiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver.
  • Sequence similaritiesBelongs to the CREC family.
    Contains 6 EF-hand domains.
  • Cellular localizationEndoplasmic reticulum lumen. Secreted. Melanosome. Sarcoplasmic reticulum lumen. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

References for Recombinant Human Calumenin protein (ab116401)

ab116401 has not yet been referenced specifically in any publications.

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