Recombinant human CaMKI gamma protein (ab61917)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab61917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Biological activitySpecific Activity 151 nmol phosphate incorporated into Autocamtide 2 per minute per mg protein at 30ºC for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay).
  • Applications

    SDS-PAGE

    Functional Studies

  • Purity> 90 % SDS-PAGE.
    Purity > 90% as determined by SDS-PAGE and Coomassie blue staining.
  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Calcium/calmodulin dependent protein kinase type 1G
    • Calcium/calmodulin-dependent protein kinase I-gamma
    • Calcium/calmodulin-dependent protein kinase Ig
    • Calcium/calmodulin-dependent protein kinase type 1G
    • CaM kinase I gamma
    • CaM kinase IG
    • CaM-KI gamma
    • CaMK like CREB kinase III
    • CaMK-like CREB kinase III
    • Camk1g
    • CaMKI gamma
    • CaMKIG
    • CLICK III
    • CLICK3
    • dJ272L16.1
    • KCC1G_HUMAN
    • VWS1
    see all
  • FunctionCalcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
  • Tissue specificityMainly expressed in brain with small amounts in skeletal muscles, kidney, spleen and liver. Strongly expressed in forebrain neocortex, striatum and limbic system.
  • Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 1 protein kinase domain.
  • DomainThe autoinhibitory domain overlaps with the calmodulin binding region and interacts in the inactive folded state with the catalytic domain as a pseudosubstrate.
  • Post-translational
    modifications
    May be prenylated on Cys-473.
  • Cellular localizationCytoplasm. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt

Recombinant human CaMKI gamma protein images

  • ab61917 on SDS-PAGE.
  • ab61917 Kinase activity assay.

References for Recombinant human CaMKI gamma protein (ab61917)

ab61917 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab61917.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"