The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Caspase 2 apoptosis related cysteine peptidase
Caspase-2 subunit p12
ICH 1 protease
Neural precursor cell expressed developmentally down-regulated protein 2
Protein phosphatase 1 regulatory subunit 57
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
Belongs to the peptidase C14A family. Contains 1 CARD domain.
The mature protease can process its own propeptide, but not that of other caspases.