Recombinant human Caspase 5 protein (ab52109)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human

Associated products

Specifications

Our Abpromise guarantee covers the use of ab52109 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Functional Studies

  • Purity
    > 95 % SDS-PAGE.

  • Form
    Lyophilised
  • Additional notes

    Active caspase-5 is useful in studying enzyme regulation, determining target substrates, screening caspase inhibitors, or as a positive control in caspase activity assays. Recommend using 1 unit/assay for analyzing caspase activity.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Constituent: ddH20

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute to 1 unit per µl in ddH2O. Lyophilized caspase-5 is stable for 1 year at –70oC. Following reconstitution, the enzyme should be aliquoted and immediately stored at –70oC.

General Info

  • Alternative names
    • Apoptosis related cysteine protease
    • CASP-5
    • CASP5
    • CASP5_HUMAN
    • Caspase-5 subunit p10
    • ICE(rel)-III
    • ICERELIII
    • ICH 3
    • ICH 3 protease
    • Protease ICH-3
    • Protease TY
    • TY
    • TY protease
    see all
  • Function
    Mediator of programmed cell death (apoptosis).
  • Tissue specificity
    Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.
  • Sequence similarities
    Belongs to the peptidase C14A family.
    Contains 1 CARD domain.
  • Post-translational
    modifications
    The two subunits are derived from the precursor sequence by an autocatalytic mechanism.
  • Information by UniProt

References

ab52109 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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