Epididymis secretory sperm binding protein Li 130P
HEL S 130P
Lysosomal aspartyl peptidase
Lysosomal aspartyl protease
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Expressed in the aorta extrcellular space (at protein level).
Involvement in disease
Ceroid lipofuscinosis, neuronal, 10
Belongs to the peptidase A1 family. Contains 1 peptidase A1 domain.
N- and O-glycosylated.
Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).