The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 µg/µl.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
Cbx4 chromobox homolog 4 (Drosophila Pc class)
Chromobox homolog 4
Chromobox homolog 4 (Pc class homolog, Drosophila)
Chromobox protein homolog 4
E3 SUMO protein ligase CBX 4
E3 SUMO protein ligase CBX4
E3 SUMO-protein ligase CBX4
NS5ATP1 binding protein 16
Pc class 2 homolog
Pc class homolog
Pc class homolog Drosophila
Polycomb 2 homolog
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Protein modification; protein sumoylation.
Contains 1 chromo domain.
Phosphorylated on Thr-497 by HIPK2 upon DNA damage; which enhances E3 SUMO-protein ligase activity and promotes sumoylation on Lys-494.