The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
C C motif chemokine ligand 21
C-C motif chemokine 21
Chemokine (C-C motif) ligand 21
Chemokine CC motif ligand 21
Efficient Chemoattractant for Lymphocytes
Secondary lymphoid-tissue chemokine
Small inducible cytokine A21
Small inducible cytokine subfamily A (Cys-Cys), member 21
Small-inducible cytokine A21
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen.
Belongs to the intercrine beta (chemokine CC) family.