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Amino Acid Sequence
MASMTGGQQMGRGHHHHHHGNLYFQGGEFWYTVNSAYGDTIIIPCRLDVP QNLMFGKWKYEKPDGSPVFIAFRSSTKKSVQYDDVPEYKDRLNLSENYTL SISNARISDEKRFVCMLVTEDNVFEAPTIVKVFKQPSKPEIVSKALFLET EQLKKLGDCISEDSYPDGNITWYRNGKVLHPLEGAVVIIFKKEMDPVTQL YTMTSTLEYKTTKADIQMPFTCSVTYYGPSGQKTIHSEQAVFDIYYPTEQ VTIQVLPPKNAIKEGDNITLKCLGNGNPPPEEFLFYLPGQPEGIRSSNTY TLTDVRRNATGDYKCSLIDKKSMIASTAITVHYLDLSLNPSGEVTRQIGD ALPVSCTISASRNATVVWMKDNIRLRSSPSFSSLHYQDAGNYVCETALQE VEGLKKRESLTLIVEGKPQIKMTKKTDPSGLSKTIICHVEGFPKPAIQWT ITGSGSVINQTEESPYINGRYYSKIIISPEENVTLTCTAENQLERTVNSL NVSAISIPEHDEADEISDENREKVNDQAK
59 kDa including tags
28 to 527
His tag N-Terminus
T7 tag N-Terminus
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituent: 0.32% Tris-HCl buffer Note: Contains, NaCl, KCl, EDTA, arginine, DTT and Glycerol.
Activated leukocyte cell adhesion molecule
Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system.
Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
The CD6 binding site is located in the N-terminal Ig-like domain.
Information by UniProt
has not yet been referenced specifically in any publications.
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