Recombinant Human CD68 protein (ab38260)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab38260 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

General Info

  • Alternative names
    • CD 68
    • CD68
    • CD68 antigen
    • CD68 molecule
    • CD68_HUMAN
    • DKFZp686M18236
    • gp11
    • Gp110
    • LAMP4
    • MACROPHAGE ANTIGEN CD68
    • Macrophage antigen CD68 (microsialin)
    • Macrosialin
    • SCARD1
    • Scavenger receptor class D member 1
    see all
  • FunctionCould play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • Tissue specificityHighly expressed by blood monocytes and tissue macrophages. Also expressed in lymphocytes, fibroblasts and endothelial cells. Expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites.
  • Sequence similaritiesBelongs to the LAMP family.
  • Post-translational
    modifications
    N- and O-glycosylated.
  • Cellular localizationCell membrane and Endosome membrane. Lysosome membrane.
  • Information by UniProt

References for Recombinant Human CD68 protein (ab38260)

ab38260 has not yet been referenced specifically in any publications.

Product Wall

Vielen Dank für Ihren Anruf von gestern.

Es tut mir leid, dass Ihre Versuche mit dem ab38260 bisher nicht so wie erwartet waren. Bitte zögern Sie nicht, uns die Details des Versuches mitzuteilen, sodass wir Ihnen eventuell technisch...

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Vielen Dank für Ihren Anruf von gestern.

Leider hat das Labor dieses Protein nicht in funktionellen Tests getestet. Ich kann Ihnen desshalb leider keine zusätzlichen Informationen zu der Nutzung dieses Proteins geben.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"