Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      MKHHHHHHASMVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERM EQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQ LRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDS EEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYL VIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTK IKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPG GLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSG LWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
    • Molecular weight
      46 kDa including tags
    • Amino acids
      1 to 378
    • Tags
      His tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab101118 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

  • Form
    Lyophilised
  • Additional notes
    Store lyophilized protein at –20°C. Lyophilized protein is unstable at 4°C and at RT. Lyophilized protein remains stable until the expiry date when stored at –20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time unlike the lyophilized protein; it does not show any change after one week at 4°C. If not stored at –20°C the protein must be reconstituted to remain stable.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 20mM Tris, pH 7.5

  • Reconstitution
    Add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

General Info

  • Alternative names
    • CDC 37
    • Cdc37
    • CDC37 cell division cycle 37 homolog
    • CDC37 cell division cycle 37 S cerevisiae homolog
    • CDC37 cell division cycle 37, S cerevisiae, homolog of
    • Cdc37 homolog
    • CDC37 protein
    • CDC37_HUMAN
    • CDC37A
    • cell division cycle 37
    • Cell division cycle 37 homolog
    • Hsp90 chaperone protein kinase targeting subunit
    • Hsp90 chaperone protein kinase targeting subunit p50Cdc37
    • Hsp90 chaperone protein kinase-targeting subunit
    • Hsp90 co chaperone Cdc37
    • Hsp90 co-chaperone Cdc37
    • p50
    • p50Cdc37
    • S cerevisiae hypothetical protein CDC37
    see all
  • Function
    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
  • Sequence similarities
    Belongs to the CDC37 family.
  • Post-translational
    modifications
    Constitutively sumoylated by UBE2I.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Images

  • 14% SDS-PAGE analysis of ab101118
    Lane 1: Molecular weight markers 14, 21, 31, 45, 66, 97 kDa
    Lane 2: ab101118 (reduced and heated, 5µg/lane)
    Lane 3: ab101118 (non-reduced and non-heated, 5µg/lane)

References

ab101118 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab101118.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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