Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MVDYSVWDHI EVSDDEDETH PNIDTASLFR WRHQARVERM EQFQKEKEEL DRGCRECKRK VAECQRKLKE LEVAEGGKAE LERLQAEAQQ LRKEERSWEQ KLEEMRKKEK SMPWNVDTLS KDGFSKSMVN TKPEKTEEDS EEVREQKHKT FVEKYEKQIK HFGMLRRWDD SQKYLSDNVH LVCEETANYL VIWCIDLEVE EKCALMEQVA HQTIVMQFIL ELAKSLKVDP RACFRQFFTK IKTADRQYME GFNDELEAFK ERVRGRAKLR IEKAMKEYEE EERKKRLGPG GLDPVEVYES LPEELQKCFD VKDVQMLQDA ISKMDPTDAK YHMQRCIDSG LWVPNSKASE AKEGEEAGPG DPLLEAVPKT GDEKDVSV

Specifications

Our Abpromise guarantee covers the use of ab78881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab78881 is purified using conventional chromatography techniques. Endotoxin Level: < 1.0 EU per 1µg of protein (determined by LAL method)
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris, pH 8.0

General Info

  • Alternative names
    • CDC 37
    • Cdc37
    • CDC37 cell division cycle 37 homolog
    • CDC37 cell division cycle 37 S cerevisiae homolog
    • CDC37 cell division cycle 37, S cerevisiae, homolog of
    • Cdc37 homolog
    • CDC37 protein
    • CDC37_HUMAN
    • CDC37A
    • cell division cycle 37
    • Cell division cycle 37 homolog
    • Hsp90 chaperone protein kinase targeting subunit
    • Hsp90 chaperone protein kinase targeting subunit p50Cdc37
    • Hsp90 chaperone protein kinase-targeting subunit
    • Hsp90 co chaperone Cdc37
    • Hsp90 co-chaperone Cdc37
    • p50
    • p50Cdc37
    • S cerevisiae hypothetical protein CDC37
    see all
  • Function
    Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
  • Sequence similarities
    Belongs to the CDC37 family.
  • Post-translational
    modifications
    Constitutively sumoylated by UBE2I.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Recombinant Human Cdc37 protein images

  • 15% SDS-PAGE showing ab78881 at approximately 45kDa (3µg).
  • All lanes : Anti-Cdc37 antibody (ab61773) at 1/1000 dilution

    Lane 1 : Recombinant Human Cdc37 protein (ab78881) at 0.1 µg
    Lane 2 : Recombinant Human Cdc37 protein (ab78881) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

References for Recombinant Human Cdc37 protein (ab78881)

ab78881 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab78881.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up