Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MPAKTPIYLKAANNKKGKKFKLRDILSPDMISPPLGDFRHTIHIGKEGQH DVFGDISFLQGNYELLPGNQEKAHLGQFPGHNEFFRANSTSDSVFTETPS PVLKNAISLPTIGGSQALMLPLLSPVTFNSKQESFGPAKLPRLSCEPVME EKAQEKSSLLENGTVHQGDTSWGSSGSASQSSQGRDSHSSSLSEQYPDWP AEDMFDHPTPCELIKGKTKSEESLSDLTGSLLSLQLDLGPSLLDEVLNVM DKNK
    • Amino acids
      1 to 254
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab161060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Binder of Rho GTPases 2
    • BORG2
    • CDC42 effector protein (Rho GTPase binding) 3
    • Cdc42 effector protein 3
    • CEP3
    • CRIB containing BORG2 protein
    • MSE55 related Cdc42 binding protein
    • MSE55 related protein
    • UB1
    see all
  • Relevance
    CDC42EP3 is probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. It induces pseudopodia formation in fibroblasts.
  • Cellular localization
    Endomembrane system; Peripheral membrane protein. Cytoplasm; cytoskeleton.

Images

  • ab161060 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

This product has been referenced in:
  • Calvo F  et al. Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts. Cell Rep 13:2699-714 (2015). Read more (PubMed: 26711338) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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