Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab71474 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM PMSF, pH 7.5

General Info

  • Alternative names
    • CDI1
    • Cdk associated protein phosphatase
    • CDK2 associated dual specificity phosphatase
    • CDK2-associated dual-specificity phosphatase
    • CDKN3
    • CDKN3_HUMAN
    • CIP2
    • Cyclin dependent kinase inhibitor 3
    • Cyclin dependent kinase interacting protein 2
    • Cyclin dependent kinase interactor 1
    • Cyclin-dependent kinase inhibitor 3
    • Cyclin-dependent kinase interactor 1
    • Cyclin-dependent kinase-interacting protein 2
    • FLJ25787
    • KAP
    • KAP1
    • Kinase associated phosphatase
    • Kinase-associated phosphatase
    • MGC70625
    • OTTHUMP00000178991
    see all
  • FunctionMay play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
  • Involvement in diseaseDefects in CDKN3 are found in patients with hepatocellular carcinoma (HCC) [MIM:114550].
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family.
  • Cellular localizationCytoplasm > perinuclear region.
  • Information by UniProt

Recombinant Human CDKN3 protein images

  • SDS-PAGE showing ab71474 at approximately 51kDa.

References for Recombinant Human CDKN3 protein (ab71474)

ab71474 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab71474.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"