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Source Baculovirus infected Sf9 cells
Amino Acid Sequence
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 25% Glycerol, 50mM Sodium chloride, 50mM Tris HCl, 0.25mM DTT, 0.1mM PMSF, pH 7.5
Cdk associated protein phosphatase
CDK2 associated dual specificity phosphatase
Function May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Involvement in disease Defects in CDKN3 are found in patients with hepatocellular carcinoma (HCC) [MIM:114550].
Sequence similarities Belongs to the protein-tyrosine phosphatase family.
Cellular localization Cytoplasm > perinuclear region.
Information by UniProt
Recombinant Human CDKN3 protein images
References for Recombinant Human CDKN3 protein (ab71474)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"