Overview

Description

  • Nature
    Recombinant
  • Source
    HEK 293 cells
  • Amino Acid Sequence
    • Accession
      O95813
    • Species
      Human
    • Sequence
      TRHQDGRQNQSSLSPVLLPRNQRELPTGNHEEAEEKPDLFVAVPHLVGTS PAGEGQRQREKMLSRFGRFWKKPEREMHPSRDSDSEPFPPGTQSLIQPID GMKMEKSPLREEAKKFWHHFMFRKTPASQGVILPIKSHEVHWETCRTVPF SQTITHEGCEKLVVQNNLCFGKCGSVHFPGAAQHSHTSCSHCLPAKFTTM HLPLNCTELSSVIKVVMLVEECQCKVKTEHEDGHILHAGSQDSFIPGVSA VDHHHHHH
    • Molecular weight
      29 kDa including tags
    • Amino acids
      18 to 267
    • Tags
      His tag C-Terminus

Specifications

Our Abpromise guarantee covers the use of ab152052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    HPLC

  • Endotoxin level
    < 1.000 Eu/µg
  • Purity
    >95% by SDS-PAGE .
    Purity is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
  • Form
    Lyophilised
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

    Constituent: 0.12% Acetic acid

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. Dissolve the lyophilized protein in 1X PBS. It is not recommended to reconstitute to a concentration less than 100 µg/ml.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days. For long term storage aliquot and store at < -20°C.

General Info

  • Alternative names
    • CER 1
    • cer1
    • CER1_HUMAN
    • Cerberus
    • Cerberus 1
    • Cerberus 1 (Xenopus laevis) homolog (cysteine knot superfamily)
    • Cerberus 1 cysteine knot superfamily homolog (Xenopus laevis)
    • Cerberus related 1
    • Cerberus related protein
    • Cerberus-related protein
    • Cerberus1
    • DAN domain family member 4
    • DAND 4
    • DAND4
    • MGC119894
    • MGC119895
    • MGC96951
    see all
  • Function
    Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak.
  • Sequence similarities
    Belongs to the DAN family.
    Contains 1 CTCK (C-terminal cystine knot-like) domain.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Secreted.
  • Information by UniProt

References

ab152052 has not yet been referenced specifically in any publications.

Publishing research using ab152052? Please let us know so that we can cite the reference in this datasheet.

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