The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Protein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl
carbohydrate response element binding protein
Carbohydrate responsive element binding protein
Class D basic helix-loop-helix protein 14
MLX interacting protein like
Williams Beuren syndrome chromosome region 14
Williams Beuren syndrome chromosome region 14 protein
Williams-Beuren syndrome chromosomal region 14 protein
WS basic helix loop helix leucine zipper protein
WS basic-helix-loop-helix leucine zipper protein
Transcriptional repressor. Binds to the canonical and non-canonical E box sequences 5'-CACGTG-3'.
Expressed in liver, heart, kidney, cerebellum and intestinal tissues.
Involvement in disease
Note=WBSCR14 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of WBSCR14 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.