Recombinant Human Chromogranin A protein (ab85339)

Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman
    • SequenceMLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME

Specifications

Our Abpromise guarantee covers the use of ab85339 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    ab85339 is purified using conventional chromatography techniques. Endotoxin Level: < 1.0 EU per 1 µg of protein (determined by LAL method).
  • FormLiquid
  • Additional notes


    Vasostatin 2 is the N-terminal fragment (19-131 aa) derived from the cleavage of chromogranin A (CgA) which is a member of the chromogranin/secretogranin(granins) family of neuroendocrine secretory proteins. Vasostatin 2 has been shown to exert several biological activities on several tissues and organs and exerts a large spectrum of homeostatic actions, including antifungal and antimicrobial effect, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

General Info

  • Alternative names
    • beta Granin
    • betagranin (N-terminal fragment of chromogranin A)
    • catestatin
    • CgA
    • CHG A
    • Chga
    • chromofungin
    • Chromogranin A parathyroid secretory protein 1
    • Chromogranin A precursor
    • ChromograninA
    • CMGA_HUMAN
    • ER-37
    • Pancreastatin
    • Parastatin
    • Parathyroid secretory protein 1
    • Pituitary secretory protein I
    • Secretory protein I
    • SP I
    • SP-I
    • SP1
    • SPI
    • Vasostatin
    • Vasostatin I
    • Vasostatin II
    see all
  • FunctionPancreastatin strongly inhibits glucose induced insulin release from the pancreas.
  • Sequence similaritiesBelongs to the chromogranin/secretogranin protein family.
  • Post-translational
    modifications
    Sulfated on tyrosine residues and/or contains sulfated glycans.
    O-glycosylated with core 1 or possibly core 8 glycans.
  • Cellular localizationSecreted. Neuroendocrine and endocrine secretory granules.
  • Information by UniProt

Recombinant Human Chromogranin A protein images

  • 15% SDS-PAGE showing ab85339 at approximately 12.8kDa (3µg).

References for Recombinant Human Chromogranin A protein (ab85339)

ab85339 has not yet been referenced specifically in any publications.

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