Recombinant Human CHTF18 protein (ab163755)

Overview

  • Product name
    Recombinant Human CHTF18 protein
  • Protein length
    Protein fragment

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      GVHRPAPRNHEQRLEHIMRRAAREEQPEKDFFGRVVVRSTAVPSAGDTAP EQDSVERRMGTAVGRSEVWFRFNEGVSNAVRRSLYIRDLL
    • Amino acids
      886 to 975
    • Tags
      proprietary tag N-Terminus

Specifications

Our Abpromise guarantee covers the use of ab163755 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Western blot

    ELISA

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • 6030457M03Rik
    • C16orf41
    • C321D2.2
    • C321D2.3
    • C321D2.4
    • CHL12
    • chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
    • Chromosome transmission fidelity protein 18 homolog
    • chtf18
    • Ctf18
    • CTF18_HUMAN
    • hCTF18
    • MGC38008
    • RUVBL
    see all
  • Function
    Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single-stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18-RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH.
  • Sequence similarities
    Belongs to the activator 1 small subunits family. CTF18 subfamily.
  • Cellular localization
    Nucleus. Associates with chromatin during S phase.
  • Information by UniProt

Images

  • ab163755 on a 12.5% SDS-PAGE stained with Coomassie Blue.

References

ab163755 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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