The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Apoptosis inhibitor 1
Baculoviral IAP repeat containing 2
Baculoviral IAP repeat containing protein 2
Baculoviral IAP repeat-containing protein 2
IAP homolog B
Inhibitor of apoptosis protein 2
NFR2 TRAF signalling complex protein
RING finger protein 48
TNFR2 TRAF signaling complex protein 2
TNFR2-TRAF-signaling complex protein 2
FunctionApoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Tissue specificityPresent in many fetal and adult tissues. Mainly expressed in adult skeletal muscle, thymus, testis, ovary, and pancreas, low or absent in brain and peripheral blood leukocytes.
Sequence similaritiesBelongs to the IAP family. Contains 3 BIR repeats. Contains 1 CARD domain. Contains 1 RING-type zinc finger.