The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Best use within three months from the date of receipt of this protein.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.31% Glutathione, 0.79% Tris HCl Note: Glutathione is reduced
Apoptosis inhibitor 2
Baculoviral IAP repeat containing 3
Baculoviral IAP repeat containing protein 3
Baculoviral IAP repeat-containing protein 3
IAP homolog C
Inhibitor of apoptosis protein 1
Mammalian IAP homolog C
RING finger protein 49
TNFR2 TRAF signaling complex protein 1
TNFR2 TRAF signalling complex protein
TNFR2-TRAF-signaling complex protein 1
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
Involvement in disease
Note=A chromosomal aberration involving BIRC3 is recurrent in low-grade mucosa-associated lymphoid tissue (MALT lymphoma). Translocation t(11;18)(q21;q21) with MALT1. This translocation is found in approximately 50% of cytogenetically abnormal low-grade MALT lymphoma.
Belongs to the IAP family. Contains 3 BIR repeats. Contains 1 CARD domain. Contains 1 RING-type zinc finger.