Overview

Description

  • NatureRecombinant
  • SourceEscherichia coli
  • Amino Acid Sequence
    • SpeciesHuman

Specifications

Our Abpromise guarantee covers the use of ab38229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    ELISA

    Western blot

  • Purity> 95 % SDS-PAGE.

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5

General Info

  • Alternative names
    • CDK2-interacting protein
    • CINP
    • CINP protein
    • CINP_HUMAN
    • Cyclin dependent kinase 2 interacting protein
    • Cyclin-dependent kinase 2-interacting protein
    • MGC849
    see all
  • FunctionInteracts with the components of the replication complex and 2 kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication. Regulates ATR-mediated checkpoint signaling.
  • Sequence similaritiesBelongs to the CINP family.
  • Post-translational
    modifications
    Phosphorylated by CDC7 but not by CDK2.
  • Cellular localizationNucleus. Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
  • Information by UniProt

Recombinant Human CINP protein images

  • Analysis of CINP Recombinant protein, the purified protein shows a band at 28 kDa. Commassie blue stained gel. Endogenous CINP is predicted to display a band of ~24kDa.

References for Recombinant Human CINP protein (ab38229)

ab38229 has not yet been referenced specifically in any publications.

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