Recombinant human CKII alpha protein (ab60763)

Overview

Description

  • NatureRecombinant
  • SourceBaculovirus infected Sf9 cells
  • Amino Acid Sequence
    • SpeciesHuman

Associated products

Specifications

Our Abpromise guarantee covers the use of ab60763 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Functional Studies

    SDS-PAGE

  • Purity> 95 % SDS-PAGE.
    Purity: >95% as determined by densitometry.
  • FormLiquid
  • Additional notes

    ab91092 (Cow Casein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

General Info

  • Alternative names
    • Casein kinase 2 alpha 1 polypeptide
    • Casein kinase II alpha 1
    • Casein kinase II alpha 1 subunit
    • Casein kinase II alpha subunit
    • Casein kinase II subunit alpha
    • CK II
    • CK II alpha
    • CK2 alpha
    • CK2 catalytic subunit alpha
    • CK2A1
    • CKII
    • CKIIalpha
    • CSK21_HUMAN
    • CSNK2A1
    see all
  • FunctionCasein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
  • Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Recombinant human CKII alpha protein images

  • Sample Kinase Activity Plot.
  • ab60763 on SDS-PAGE, MW ~70kDa.

References for Recombinant human CKII alpha protein (ab60763)

ab60763 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"