This product is an active protein and may elicit a biological response in vivo, handle with caution.
Casein kinase 2 alpha 1 polypeptide
Casein kinase II alpha 1
Casein kinase II alpha 1 subunit
Casein kinase II alpha subunit
Casein kinase II subunit alpha
CK II alpha
CK2 catalytic subunit alpha
FunctionCasein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.
Sequence similaritiesBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. Contains 1 protein kinase domain.