Recombinant Human Claudin 4 protein (ab112274)

Overview

Description

  • NatureRecombinant
  • SourceWheat germ
  • Amino Acid Sequence
    • AccessionO14493
    • SpeciesHuman
    • SequenceMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQCKVYDSLLALPQDLQ
    • Molecular weight31 kDa including tags
    • Amino acids29 to 78

Specifications

Our Abpromise guarantee covers the use of ab112274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

    Western blot

    ELISA

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Claudin-4
    • Claudin4
    • CLD4_HUMAN
    • CLDN 4
    • CLDN4
    • Clostridium perfringens enterotoxin receptor
    • Clostridium perfringens enterotoxin receptor 1
    • CPE R
    • CPE receptor
    • CPE-R
    • CPE-receptor
    • CPER
    • CPETR
    • CPETR 1
    • CPETR1
    • hCPE R
    • WBSCR8
    • Williams Beuren syndrome chromosome region 8 protein
    • Williams-Beuren syndrome chromosomal region 8 protein
    see all
  • FunctionPlays a major role in tight junction-specific obliteration of the intercellular space.
  • Involvement in diseaseNote=CLDN4 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • Sequence similaritiesBelongs to the claudin family.
  • Cellular localizationCell junction > tight junction. Cell membrane.
  • Information by UniProt

Recombinant Human Claudin 4 protein images

  • 12.5% SDS-PAGE showing ab112274 at approximately 31.13kDa stained with Coomassie Blue.

References for Recombinant Human Claudin 4 protein (ab112274)

ab112274 has not yet been referenced specifically in any publications.

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