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Source Baculovirus infected Sf21 cells
Amino Acid Sequence
Tags His tag N-Terminus Specifications
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activity Specific Activity: minimum 8,000 units per mg protein
Additional notes This protein is relatively unstable at room temperature; Keep the enzyme on ice (0 °C to 4 °C) at all times.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
Preservative: 300µM diethyldithio-carbamate (DDC)
Constituents: 0.1% Tween 20, 80mM Tris HCl, pH 8
Note: If this preservative (DDC) is undesirable, it can be removed by standard desalting procedures, but the enzyme is unstable in the absence of the preservative and so should be used within one hour.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
Function Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Pathway Lipid metabolism; prostaglandin biosynthesis.
Sequence similarities Belongs to the prostaglandin G/H synthase family. Contains 1 EGF-like domain.
Post-translational modifications S-nitrosylation by NOS2 (iNOS) activates enzme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-561.
Cellular localization Microsome membrane. Endoplasmic reticulum membrane.
Information by UniProt
Recombinant human COX2 / Cyclooxygenase 2 protein images
Sandwich ELISA - COX2 / Cyclooxygenase 2 protein (His tag) (ab58868)
Standard curve for COX2 / Cyclooxygenase 2 (Analyte: ab58868); dilution range 1pg/ml to 1µg/ml using Capture Antibody ab90345 at 1µg/ml and Detector Antibody ab15191 at 0.5µg/ml.
References for Recombinant human COX2 / Cyclooxygenase 2 protein (ab58868)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"