The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab119161 is purified by proprietary chromatographic techniques. Purity was determined to be greater than 95% as determined by RP-HPLC and SDS-PAGE.
Additional notesStore at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD
Protein kinase C-potentiated inhibitor protein of 17 kDa
Protein phosphatase 1
Protein phosphatase 1 regulatory (inhibitor) subunit 14A
Protein phosphatase 1 regulatory subunit 14A
Regulatory subunit 14A
FunctionInhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Tissue specificityIsoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Sequence similaritiesBelongs to the PP1 inhibitor family.