Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD
Protein kinase C-potentiated inhibitor protein of 17 kDa
Protein phosphatase 1
Protein phosphatase 1 regulatory (inhibitor) subunit 14A
Protein phosphatase 1 regulatory subunit 14A
Regulatory subunit 14A
FunctionInhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Tissue specificityIsoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
Sequence similaritiesBelongs to the PP1 inhibitor family.