Recombinant Human CPI17 alpha protein (ab75206)

Overview

Description

  • Nature
    Recombinant
  • Source
    Escherichia coli
  • Amino Acid Sequence
    • Species
      Human
    • Sequence
      MGSSHHHHHH SSGLVPRGSH MAAQRLGKRV LSKLQSPSRA RGPGGSPGGL QKRHARVTVK YDRRELQRRL DVEKWIDGRL EELYRGMEAD MPDEINIDEL LELESEEERS RKIQGLLKSC GKPVEDFIQE LLAKLQGLHR QPGLRQPSPS HDGSLSPLQD RARTAHP

Specifications

Our Abpromise guarantee covers the use of ab75206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    SDS-PAGE

  • Purity
    > 95 % SDS-PAGE.
    ab75206 is purified by using conventional chromatography techniques.
  • Form
    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris, 2mM EDTA, 1mM DTT, pH 8.0

General Info

  • Alternative names
    • 17 kDa PKC-potentiated inhibitory protein of PP1
    • 17-KDa protein
    • 17kDa PKC potentiated inhibitory protein of PP1
    • CPI 17
    • CPI 17 alpha
    • CPI 17alpha
    • CPI-17
    • CPI17
    • PKC potentiated inhibitory protein of PP1
    • PKC potentiated inhibitory protein of PP1, 17-KD
    • PP14A_HUMAN
    • PPP1INL
    • Ppp1r14a
    • Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD
    • Protein kinase C-potentiated inhibitor protein of 17 kDa
    • Protein phosphatase 1
    • Protein phosphatase 1 regulatory (inhibitor) subunit 14A
    • Protein phosphatase 1 regulatory subunit 14A
    • Regulatory subunit 14A
    see all
  • Function
    Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
  • Tissue specificity
    Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta.
  • Sequence similarities
    Belongs to the PP1 inhibitor family.
  • Cellular localization
    Cytoplasm.
  • Information by UniProt

Recombinant Human CPI17 alpha protein images

  • 15% SDS-PAGE showing ab75206 at approximately 18kDa. (3µg)

References for Recombinant Human CPI17 alpha protein (ab75206)

ab75206 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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