Overview

Description

  • Nature
    Recombinant
  • Source
    Wheat germ
  • Amino Acid Sequence
    • Accession
    • Species
      Human
    • Sequence
      VFKNGKMGLNAEHSWADAPIVAHLWEYVMSIDSLQLGYAEDGHCKGDINP NIPYPTRLQWDIPGECQEVIETSLNTANLLANDVDFHSFP
    • Molecular weight
      36 kDa including tags
    • Amino acids
      461 to 550

Specifications

Our Abpromise guarantee covers the use of ab114450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    ELISA

    SDS-PAGE

    Western blot

  • Form
    Liquid
  • Additional notes
    Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

General Info

  • Alternative names
    • Carnitine O palmitoyltransferase 1 liver isoform
    • Carnitine O palmitoyltransferase I
    • Carnitine O palmitoyltransferase I liver isoform
    • Carnitine O-palmitoyltransferase 1
    • Carnitine O-palmitoyltransferase I
    • Carnitine palmitoyltransferase 1A
    • Carnitine palmitoyltransferase 1A (liver)
    • Carnitine palmitoyltransferase I
    • Carnitine palmitoyltransferase I liver
    • CPT 1
    • CPT I
    • CPT1
    • CPT1 L
    • CPT1-L
    • Cpt1a
    • CPT1A_HUMAN
    • CPTI
    • CPTI-L
    • L CPT1
    • liver isoform
    see all
  • Tissue specificity
    Strong expression in kidney and heart, and lower in liver and skeletal muscle.
  • Pathway
    Lipid metabolism; fatty acid beta-oxidation.
  • Involvement in disease
    Defects in CPT1A are the cause of carnitine palmitoyltransferase 1A deficiency (CPT1AD) [MIM:255120]; also known as CPT-I deficiency or CPT1A deficiency. CPT1AD is a rare autosomal recessive metabolic disorder of long-chain fatty acid oxidation characterized by severe episodes of hypoketotic hypoglycemia usually occurring after fasting or illness. Onset is in infancy or early childhood.
  • Sequence similarities
    Belongs to the carnitine/choline acetyltransferase family.
  • Cellular localization
    Mitochondrion outer membrane.
  • Information by UniProt

Images

  • ab114450 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

References

ab114450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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