The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Additional notesProtein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Preparation and Storage
Stability and Storage
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Acidic type mitochondrial creatine kinase
Creatine kinase mitochondrial 1 ubiquitous
Creatine kinase U type, mitochondrial
Creatine kinase ubiquitous mitochondrial
Creatine kinase, mitochondrial 1 (ubiquitous)
Creatine kinase, mitochondrial 1A
Creatine kinase, mitochondrial 1B
Ubiquitous mitochondrial creatine kinase
RelevanceCreatine kinase MT is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Creatine kinase MT occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.
Cellular localizationCell Membrane and Mitochondrial
Recombinant Human Creatine kinase MT protein images
SDS-PAGE - CKMT1B protein (ab114608)
ab114608 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.
References for Recombinant Human Creatine kinase MT protein (ab114608)
has not yet been referenced specifically in any publications.
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