The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.0 Constituents: 10% Glycerol, 2.4% Urea, 0.32% Tris HCl
Cofactor required for Sp1 transcriptional activation subunit 8
Cofactor required for Sp1 transcriptional activation subunit 8 (34kD)
Cofactor required for Sp1 transcriptional activation subunit 8 34kDa
CRSP complex subunit 8
Mediator complex subunit 27
Mediator of RNA polymerase II transcription subunit 27
P37 TRAP/SMCC/PC2 subunit
Transcriptional coactivator CRSP34
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Belongs to the Mediator complex subunit 27 family.